ICD code definitions

CPT® Code 81001: Urinalysis by Dip Stick or Tablet, Automated Microscopy

December 3, 2025
3 min read
CPT® Code 81001

Overview
CPT® Code 81001 is used to report automated urinalysis performed using a dip stick or tablet method, with automatic microscopy. This test evaluates multiple urinary parameters including pH, protein, glucose, ketones, blood, and more, and is often used for screening, diagnosis, or monitoring of renal, metabolic, or systemic conditions.

The code represents the laboratory test itself; interpretation, patient counseling, or medical decision-making is billed separately.

Key Facts About CPT® 81001

  • Service type: Clinical laboratory urinalysis
  • Provider type: Physicians, laboratories, and qualified healthcare professionals
  • Medical services included: Automated dip stick/tablet urinalysis with microscopy
  • Specimen type: Urine (freshly collected)
  • Common clinical indications:
    • Screening for urinary tract infection (UTI) or hematuria
    • Monitoring chronic kidney disease or diabetes
    • Assessing metabolic or electrolyte disorders
    • Evaluating proteinuria or other renal abnormalities

When to Use CPT® 81001

CPT 81001 is appropriate when:

  • Urine is collected and analyzed using automated dip stick/tablet methods with automated microscopy
  • The test is medically necessary to evaluate, screen, or monitor urinary or systemic conditions
  • Results will influence diagnosis, treatment, or monitoring

Examples:

  • Routine urinalysis for a patient with diabetes to monitor microalbuminuria
  • Evaluation of suspected urinary tract infection with automated microscopy
  • Screening for renal disease during a wellness exam

Documentation Requirements

To properly support CPT 81001 billing, documentation should include:

  • Patient identifiers and date of collection
  • Method of analysis (automated dip stick or tablet)
  • Whether automated microscopy was performed
  • Indication for testing (screening, diagnosis, monitoring)
  • Test results and follow-up recommendations

Accurate documentation ensures proper reimbursement, compliance, and longitudinal tracking in the patient’s record.

Reimbursement and Coding Considerations

  • CPT 81001 is generally covered by commercial insurers, Medicare, and Medicaid when medically necessary
  • Interpretation or patient counseling is not included and billed separately
  • Modifier use may be required if multiple lab tests are performed on the same specimen
  • Always verify payer-specific policies for urinalysis and bundled testing

How OptiMantra Supports Urinalysis and Lab Management

OptiMantra’s integrated EMR and practice management system streamlines workflow for CPT 81001 testing:

With OptiMantra, providers can:

  • Automatically link urinalysis orders to the patient’s chart
  • Track results over time for longitudinal monitoring
  • Document test indications and follow-up plans directly in the EMR
  • Generate audit-ready, compliant billing codes
  • Integrate urinalysis results into broader patient care plans

By centralizing lab tracking, documentation, and billing, OptiMantra ensures accuracy, compliance, and smooth workflows for urinalysis services.

Try OptiMantra for free here!

Jessica Castro
Jessica Castro

Jessica is a Massachusetts-based LPN with 13+ years of experience in patient care, healthcare technology, and education. As the Implementation and Customer Success Manager at OptiMantra, she helps providers optimize EMR solutions for better workflows and patient outcomes. With a Bachelor's in Community Health and a Master's in Healthcare Innovation in progress, she is passionate about leveraging technology to improve care delivery. Through her writing, she shares insights on healthcare best practices, EHR optimization, and patient advocacy to support providers in delivering exceptional care.