ICD code definitions

CPT® Code 84144: Progesterone Test

September 22, 2025
3 min read
CPT® Code 84144

Description:
CPT® code 84144 is used for the quantitative measurement of progesterone levels in a patient’s serum. Progesterone is a key reproductive hormone that plays an essential role in the menstrual cycle, fertility, and pregnancy maintenance. Measuring progesterone helps evaluate ovulation, monitor early pregnancy health, and assess hormonal balance in both women and men.

When to Use:
Use CPT 84144 when testing is indicated for:

  • Assessing ovulation in infertility evaluations or confirming luteal phase function.
  • Monitoring early pregnancy or evaluating risk of miscarriage.
  • Diagnosing menstrual irregularities, amenorrhea, or abnormal uterine bleeding.
  • Evaluating ovarian or adrenal disorders, such as cysts or tumors affecting hormone production.
  • Investigating hormonal imbalances in men related to adrenal or testicular function.

Billing Requirements:

  • Requires a serum specimen for laboratory analysis.
  • Documentation should specify the clinical indication (e.g., infertility, menstrual irregularity, pregnancy monitoring).
  • Report once per encounter unless serial testing is clinically necessary to track hormone fluctuations.
  • If ordered alongside other reproductive or endocrine tests, follow applicable panel billing guidelines.

Includes:

  • Laboratory measurement and quantification of serum progesterone levels.
  • Reporting results to the ordering provider for clinical interpretation, treatment planning, and ongoing patient management.

Tips for Practice Efficiency:
Managing hormone testing efficiently is key in reproductive and integrative medicine. With OptiMantra, providers can:

  • Automatically link progesterone results to patient charts for trend tracking and cycle-based analysis.
  • Document fertility evaluations and hormone therapy plans within customizable templates.
  • Ensure accurate coding and billing for hormonal lab tests to optimize reimbursement and minimize administrative effort.

OptiMantra streamlines endocrine and fertility workflows, enabling practices to track hormonal health seamlessly, support patient education, and deliver high-quality, evidence-based care with precision.

Try OptiMantra for free here!

Jessica Castro
Jessica Castro

Jessica is a Massachusetts-based LPN with 13+ years of experience in patient care, healthcare technology, and education. As the Implementation and Customer Success Manager at OptiMantra, she helps providers optimize EMR solutions for better workflows and patient outcomes. With a Bachelor's in Community Health and a Master's in Healthcare Innovation in progress, she is passionate about leveraging technology to improve care delivery. Through her writing, she shares insights on healthcare best practices, EHR optimization, and patient advocacy to support providers in delivering exceptional care.