CPT® code 96374 is used to report the intravenous (IV) push administration of a single therapeutic, prophylactic, or diagnostic drug or substance, not including chemotherapy or other highly complex drug infusions. This code represents a distinct procedural service that may occur during outpatient or office-based care.
What is CPT 96374?
CPT code 96374 describes an IV push injection of a drug or substance that is administered directly into a vein over a short period of time, without a concurrent infusion. This service is typically performed in clinical settings such as outpatient clinics, urgent care, or infusion centers.
It includes:
- Direct IV administration of a medication
- Supervision and preparation of the drug
- Assessment and monitoring of the patient during and after the injection
This code does not apply to injections given via intramuscular (IM), subcutaneous (SC), or intra-arterial routes.
When to report CPT 96374
You may report 96374 when:
- A non-chemotherapeutic drug is administered via IV push
- The provider or qualified staff remains present during administration
- The drug is administered as a separate service and not part of a hydration or infusion session
- Documentation includes the drug name, route, dosage, and time of administration
Billing notes and common modifiers
- CPT 96374 is often billed in conjunction with an appropriate E/M code, if a separately identifiable evaluation and management service is performed and documented. In that case, use modifier -25 with the E/M code.
- Be sure to report the specific drug(s) administered using the appropriate HCPCS Level II “J-codes.”
- This code is commonly used for medications such as antiemetics, corticosteroids, analgesics, antihistamines, or diagnostic agents delivered via IV.
Streamline Infusion and Injection Billing with OptiMantra
For practices offering IV therapies or outpatient medication administration, OptiMantra simplifies the documentation and billing of services like CPT 96374. With OptiMantra, providers can:
- Document IV push procedures directly within structured encounter templates
- Automatically link drugs administered with corresponding CPT and J-codes
- Generate accurate superbills that reflect time, route, and supervision details
- Review payer-specific rules and reimbursement guidance to reduce denials
- Track inventory and lot numbers for medications administered in-office
Whether you run a wellness center offering IV therapy or a specialty clinic delivering diagnostic injections, OptiMantra helps ensure proper coding, compliance, and operational efficiency—all from one intuitive platform.
Try OptiMantra for free here!
