ICD code definitions

CPT® Code 83520: Serum Iron Test

September 12, 2025
3 min read
CPT® Code 83520

CPT® code 83520 is used to report a laboratory test measuring serum iron levels in the blood. This test evaluates the amount of circulating iron, which is essential for red blood cell production and overall metabolic function. Serum iron testing is commonly used in diagnosing anemia, monitoring iron therapy, and assessing nutritional or chronic disease status.

When to Use CPT® Code 83520

  • When evaluating patients for iron deficiency anemia or iron overload.
  • As part of a workup for chronic fatigue, pallor, or unexplained weakness.
  • To monitor response to iron supplementation therapy.
  • Often ordered alongside total iron-binding capacity (TIBC) or ferritin tests for a complete iron profile.

Billing Requirements

  • Report per test performed.
  • Documentation should include the clinical indication for testing and relevant patient history.
  • May be performed in conjunction with other iron-related tests; bill each test with its respective CPT® code.
  • Ensure appropriate ICD-10 codes are included to support medical necessity.

Common Clinical Scenarios

  • A primary care provider orders a serum iron test for a patient with fatigue and low hemoglobin.
  • An integrative clinic monitors a patient’s response to iron therapy for iron-deficiency anemia.
  • A gastroenterologist evaluates iron status in a patient with chronic gastrointestinal blood loss.

Streamline Iron Testing with OptiMantra

Accurate documentation and billing for CPT® 83520 are essential for compliance and reimbursement. OptiMantra’s EMR and practice management platform allows providers to order lab tests, capture clinical indications, and integrate results directly into patient records. For primary care, integrative, and specialty clinics, OptiMantra simplifies lab workflows, reduces administrative burden, and ensures providers can focus on patient care.

Jessica Castro
Jessica Castro

Jessica is a Massachusetts-based LPN with 13+ years of experience in patient care, healthcare technology, and education. As the Implementation and Customer Success Manager at OptiMantra, she helps providers optimize EMR solutions for better workflows and patient outcomes. With a Bachelor's in Community Health and a Master's in Healthcare Innovation in progress, she is passionate about leveraging technology to improve care delivery. Through her writing, she shares insights on healthcare best practices, EHR optimization, and patient advocacy to support providers in delivering exceptional care.